The clinical healing effect of vacuum sealing drainage technique using in treatment of deep burn wound / 中国医师杂志

Objective To explore the healing effect of vacuum sealing drainage (VSD) technique using in treatment of deep burn wound.Methods Patients were selected who hospitalized in our hospital because of burn from June 2014 to May 2016,and divided into the VSD group and silver sulfadiazine (SD-Ag) group.The incidence of wound infection,bacterial culture positive rate and wound visual analogue score (VAS) were compared between two groups of patients in different time after burn,and also compared two groups of patients with wound healing time,and incidence of scar and the scar rating scale of vancouver.Results A total of 80 patients were included in the study,and divided into VSD (n =46) and SD-Ag (n =34) groups.The wound infection rate and bacterial culture positive rate in the VSD group were significantly lower than the SD-Ag group after burn for 7 d,14 d,and 21 d (P ＜ 0.05).Patient's wound pain VAS score in the VSD group was less than SD-Ag group after burn for 7 d,14 d,and 21 d (P ＜0.05).The wound healing time,incidence of scar,and vancouver scar table score in the VSD group were significantly lower than that of SD-Ag group (P ＜ 0.05).Conclusions The use of vacuum sealing drainage of treatment for burn patients can significantly reduce the wound infection,relieve wound pain,promote wound healing,and reduce scar occurred at the same time.

Prevention of multiple organ failure in early stage of severe burns with immediate fast fluid infusion in dogs / 第三军医大学学报

Fifty percent TBSA third degree burns was inflicted to 24 dogs and they were treated with immediate fluid infusion (8 dogs),delayed conventional infusion (n=8),and delayed fast infusion (n=8),It was found that in the immediate and delayed fast infusiong groups,strike volume,strike index, left ventricular strike work index,right ventricular strike index and femoral arterial pressure were maintained at a level more than 50% of the normal and were gradually restored.Their pulmonary artery wedge pressure was larger than 1.3 kPa.ALT and LDH were increased but never exceeded the preburn level.DB,TB,UN,Cr,PaO2,P(A-a)O2 were maintained in the normal range.MDA RCR,ADP/O,ATP,positive blood culture rate,mortality rate and morbility of multiple organ failure were all lower than those of the delayed conventional infusion group.It is believed that in the early stage of burn injury,the development of multiple organ failure can prevented effectively with immediate infusion and partially with delayed fast infusion while delayed conventional infusion exerts no protection at all.